Numerical solution of linear and nonlinear algebraic equations, and ordinary and partial differential equations. Numerical differentiation and integration. Linear and nonlinear regression analysis. Optimization methods. Applications to chemical & biomolecular engineering design-oriented problems. Excel spreadsheets are used for all computations. An introduction to Visual Basic for Applications programming is included. All applications and homework problems are related to Chemical and Biomolecular Engineering. A brief introduction to MatLab is included.